What is High-Throughput Experimentation?
HTE is a powerful approach in small molecule process development. By running dozens to hundreds of miniaturized reactions in parallel, HTE enables rapid screening of variables like catalysts, solvents, and ligands—dramatically increasing the chances of finding optimal reaction conditions with minimal input material and manual effort.
Our HTE capabilities
- Advanced Robotic Platform
- Parallel reactions: 8 to 96 at once, 1–20 mL scale
- Temperature range: -35 °C to 180 °C | Pressure: up to 120 bar
- Automated liquid/solid handling (0.1 mg resolution)
- Handles viscous liquids and gases like N₂, H₂, CO, CO₂
- Kinetic module with real-time data collection
- Controlled Environment
- Dual-chamber glove/purge box system
- Safe handling of moisture- and air-sensitive materials
- Ultra-low oxygen and water conditions (<50 ppm)
- Analytical Excellence (QC)
- Automated sample prep & filtration
- Redundant UPLC systems (PDA, MS, chiral & achiral separation)
- 24-hour turnaround for 96 reactions
- GC system with established method screening