As poorly soluble small-molecule drug candidates continue to challenge development timelines, the ability to scale spray-dried dispersions (SDDs) efficiently and reliably has become increasingly important. We combine deep scientific expertise, advanced modeling capabilities, and a proven scale-up framework to help customers overcome the complexities of SDD development. From early feasibility studies through commercial manufacturing, our integrated approach enables robust process design, minimizes risk, and helps ensure bioavailability, stability, and manufacturability.
Access our whitepaper to discover how our data-driven approach to spray-dried dispersion scale-up can accelerate development, reduce scale-up uncertainty, and support a seamless transition from laboratory studies to commercial production. The paper also includes a case study featuring a Fortune 500 pharmaceutical company that needed to maintain the bioavailability of a molecule with challenging chemical and physical properties throughout scale-up and manufacturing. By leveraging our spray-drying expertise and collaborative development approach, we helped preserve critical material attributes, reduce process risk, and successfully deliver a commercial manufacturing batch.
