In this webinar, we explore the challenges of comprehensively assessing the specificity profile when moving a candidate to first-in-human studies, through the application of membrane proteome arrays and cell-based immunotoxicity assays.
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Streamlining early phase drug development with continuous flow technologies
As small molecule complexity increases, early-stage development faces new challenges that demand...
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Designing a Plug-and-Play System to Produce Engineered Extracellular Vesicles
Extracellular vesicles (EVs), including exosomes, are being studied extensively and have emerged as...
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Plasmid Engineering and Process Development to Improve Self-Complementary AAV Productivity
Self-complementary AAV (scAAV) vectors were developed by mutating one of the ITRs to form...
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Development of high-performing stable producer cell lines for therapeutic AAV vector manufacturing
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Poster
Adeno-associated virus characterization using nanopore long read sequencing and analysis
Recombinant adeno-associated virus (rAAV) has become a leading vector for in vivo gene delivery. The...
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Large-Scale High Titer Lentiviral Production Using Lonza's Suspension Transient Transfection...
Lentivirus vector (LVV) is a major player in cell and gene therapies. It efficiently transduces both...
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Interview
Q&A on large-scale commercial expansion at Lonza's Stein facility
Are you a biopharmaceutical or biotech professional looking to stay ahead in the industry? Download...
Poster
Novel synthetic production phase promoter for enhanced titre, product quality and expression...
In this scientific poster, we demonstrate the development of a novel synthetic gene promoter...
Technical/Service brief
Novel synthetic fusion promoter for improved GS-CHO expression of biotherapeutics
Historically, advancements in CHO-based recombinant protein production have been driven...
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White paper
Navigating the development of dry powder for inhalation
Interest in pulmonary/nasal routes for local delivery has significantly increased over the last...
White paper
Innovations in linking rational design and material-sparing strategies for enabled intermediates and...
Did you catch our insightful webinar on Linking rational design and material-sparing strategies for...
Presentation (on-demand)
Challenging your AAV productivity and packaging efficiencies through a validated platform
AAV transient and stable cell line platforms represent a leap into next-generation technologies that...