The GS piggyBac® transposon system
The GS piggyBac® system uses an engineered hyperactive piggyBac® transposase enzyme to insert expression vector cargos with your gene of interest into the host cell genome with high efficiency, supporting stable piggyBac® integration, with the following benefits:
- Enhanced performance of the GS piggyBac® system is observed with low versus high expressing monoclonal antibodies
- Accommodating a large DNA cargo (> 200kb) makes the GS piggyBac® system highly suited to support cell line engineering needed to enhance complex protein expression
- Preferentially targeting genetically stable parts of the genome at high efficiency has the potential to improve cell line stability
The GS piggyBac® system inserts expression vector cargos into the host cell genome with high efficiency
Combining our GS System® platform with piggyBac® Transposon Technology can result in increased yields versus the GS System® technology platform alone. Available to new and existing GS System® platform license holders.
Talk to our experts to get to know more about the Lonza in Your Lab® offering and piggyBac® Transposon Technology.
Ask the Experts in Expression
Unlike random or low efficiency integration methods, the piggyBac® transposon system targets genetically stable genomic regions associated with high expression.
This results in:
- More predictable cell line performance
- Higher titers
- Greater stability across scaleup
- Reduced development risk
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