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  • GS piggyBac® Transposon Technology

Proven High Titers with GS piggyBac®

GS piggyBac® is a unique and versatile cell line engineering technology. Benefit from access to a proven transposon-based technology that preferentially targets stable regions of the genome associated with highly expressed genes.
Contact us
​
GS piggyBac®

The GS piggyBac® system uses an engineered hyperactive piggyBac™ transposase enzyme to insert GS Xceed® expression vector cargos with your gene of interest into the host cell genome with high efficiency with the following benefits:

  • Enhanced performance of GS piggyBac® is observed with low versus high expressing monoclonal antibodies
  • Accommodating a large DNA cargo (> 200kb) makes GS piggyBac® highly suited to support cell line engineering needed to enhance complex protein expression
  • Preferentially targeting genetically stable parts of the genome at high efficiency has the potential to improve cell line stability

GS Xceed Brochure

Download the brochure

​
Express vector cargos into the host cell genome with high efficiency

Combining our GS System®with piggyBac® Transposon Technology can result in increased yields versus GS System® alone. Available to new and existing GS System® license holders.

Contact us to learn more

From our clients

25 April 2022 - Luzhu Biotech Develops Recombinant Herpes Zoster Vaccine and Bispecific Antibody using Lonza’s GS Xceed® Gene Expression System

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Services enabled by this technology

Rapid Host Screen and Early Protein Expression
Select the optimal expression system for your biotherapeutic protein production with our Rapid Host...
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Non-GMP Manufacture: Light Path™ Discovery
Our Light Path™ Discovery Protein Production Services provide milligram to low gram quantities of...
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Mammalian Cell Line Development
Benefit from our flexible approach to cell line development matching your project’s priorities in...
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Biologics

Knowledge Center

Knowledge Center
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Bispecific Antibody Development: Upstream Challenges and Strategies
Biological pipelines are evolving from standard antibody formats to next-generation biologics such...
Technical/Service brief
GS Xceed® Gene Expression System Brochure
GS Xceed is a scalable, integrated, proven platform for developing biotherapeutics as quickly,...
Webinar on-demand
Webinar (on-demand)
Right First Time: Successfully Progressing Biotherapeutics from Discovery to the Clinic
It is essential that the best approaches and tools are selected to maximize success when moving a...
Technical/Service brief
Tools for Developing Successful Biologics - Vectors for the GS Gene Expression System®
We have developed a series of advanced vector systems with applications in producing standard...
Article
Becoming a Champion Go Player
Although antibodies, at the time of writing, still dominate the clinic, there is a definite shift in...
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