Inhalation Formulation Development Services

Bespoke Toolkit of Inhalation Methodologies

We have a global network of connected experts who turn impossible challenges into the next era of inhaled therapies.

Integrated Understanding from API to Commercial

Let our experts help you navigate every stage of the journey, with a deeper understanding of how to vastly improve yields and create a commercially viable solution.

Premier Particle Engineering Platform

Complemented by product development teams that are well versed in powder performance parameters for capsule-based devices.

Get the most appropriate inhalation formulation for your respiratory drug development

DPI technology has become the preferred approach for inhalation formulation vs. other dry powder technologies or aerosols. Lactose-blend or carrier-free based approaches to DPI require precise particle engineering through either micronization/jet milling or spray drying, respectively.

Expertise and depth of capabilities in both particle size reduction and spray drying allow our scientists to choose the most appropriate technology for your specific DPI application.

Our premier particle engineering platform is complemented by a full range of product development. Our product development teams are well versed in powder performance parameters for capsule-based devices.

Our integrated DPI offerings

Milling, spray drying
Precision micro-dosing
Screening and clinical testing
GMP testing and methods validation

First time right for your DPI target product profile

The choice between jet milling and spray drying technology is dependent upon several factors:

Lactose compatibility
Process and scale-up issues
Physical properties of the API
Particle size distribution requirements
Amount of NCE available for feasibility work
API characteristics and ability to be jet milled
Content uniformity concerns

Our scientists have the expertise and experience to rapidly identify the formulation and enabling technology required to meet your target product profile. Both particle engineering approaches continue to find broad application in inhaled formulations. However, spray drying is finding increased application in DPI approaches for larger molecules or when dispersion, nano-amorphous matrices, crystalline API in amorphous matrices, or mixed approaches are required.