Streamlined Selection of in vivo Predictive Dissolution Media

Oral administration is the most common delivery method for medicines. If a patient is to get full benefit from an oral medicine, the solid dosage form must first dissolve in their gastrointestinal (GI) fluids, and then permeate across the GI membrane. The efficient development of robust oral drug products requires biopredictive in vitro dissolution methods that can evaluate how the interplay between the drug formulation and the properties of the GI fluid impacts on performance. This webinar focuses on the design of dissolution media to support biopredictive dissolution testing, and highlights a method for selecting practical, physiologically relevant media based upon drug, formulation, and GI fluid properties.