Inhaled Bevacizumab: A case study for delivery to the lung

Bevacizumab is a monoclonal antibody VEGF-inhibitor approved for treatment of cancers, including lung and colon. The goal of this study was to perform a real-time stability study of spray-dried bevacizumab dry powder formulation out to 24 months. 

Download the poster, presented at RDD Europe 2023, to learn more.

Download
Latest content

Latest briefing from the Knowledge Center

KC Video thumbnail
Webinar (on-demand)
Improved and Rebalanced Helper and RepCap Plasmids to Ramp up your AAV Productivity
Strong growth in the recombinant AAV (rAAV)-based gene therapy sector is creating a need for...
Poster
Optimization of Packaging Efficiency for Adeno-Associated Virus by Evaluating Production Process...
Author: Tsai-Yu Chen, PhD, Senior Scientist, Process Development Abstract: The packaging...
micro image
Poster
Comparison between Droplet Digital PCR and Quantitative PCR for Adeno-Associated Virus Infectious...
Author: Tam Duong, PhD, Scientist II, R&D Abstract: Recombinant adeno-associated virus (rAAV) has...
AAV manufacturing
Poster
A New Two-Dimensional Droplet Digital PCR Method for AAV Intact Viral Genome Titer Analysis
Author: Tam Duong, PhD, Scientist II, R&D Abstract: Recombinant adeno-associated virus (rAAV) has...
Poster
A Streamlined Downstream Purification Platform Process for Adeno-Associated Viral Vectors
Author: F. Michael Haller, PhD, Principal Scientist, R&D Abstract: One major obstacle to achieving...
Poster
A Comprehensive Characterization of Full, Partial, and Empty Lentiviral Vectors
Author: Vijetha Bhat, MS, Scientist II, R&D Abstract: Lentiviral vectors are biological vehicles...
Cocoon device
Webinar (on-demand)
Choosing versatile and scalable platforms for cell therapy manufacturing
Speaker: Peter Yates, Ph.D, Product Management Director, Personalized Medicine As cell therapies...
lab workers on tablet
Podcast
CMC Challenges in the Evolving Small Molecule Development Pipeline
A growing proportion of drugs in the development pipeline nowadays start out life at small biotech...
Article
Ramp Up Your AAV Production with the Xcite™ AAV Platform Technology
With the AAV market gaining momentum, gene therapy developers are under increasing pressure to...
micro image
Technical/Service brief
Ramp up your AAV productivity with novel engineered plasmids and optimized HEK293 cell line
Lonza has established experience and capabilities in rAAV production and is continually identifying...
micro image
R&D Blog post
Developing new analytical methods for recombinant AAV viral vectors
Recombinant adeno-associated virus (rAAV) has been utilized successfully for in vivo gene delivery...
Drug Substance API-HPAPI
Presentation (on-demand)
Continuous Flow Techniques for Fine Chemical Manufacturing
For commodity chemicals, low profit margins drive the need for high-performing, cost effective, and...