During drug development, various techniques can be applied to enhance the bioavailability of small molecule drugs, which often face delivery challenges from low solubility. Manufacturers should consider the use of enabling technologies, which can reduce the amount of solvent used and allow for use of less toxic solvents to mitigate the environmental and health impact and move toward a more sustainable manufacturing process. Read this executive summary for more on how the application of novel technologies to enhance organic solubility has enabled a large step forward in sustainability for the manufacture of ASDs by spray drying.
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