A critical factor formulation experts must understand during the development of an oral solid dosage (OSD) form is that drug and dosage form properties can significantly limit the rate and extent of drug absorption and bioavailability if the OSD is not formulated with these considerations in mind. This leads to a risk of suboptimal drug delivery in the human body. In vivo dissolution testing is the gold standard for assessing oral bioperformance; however, a key component of this method is the dissolution media you use during testing.
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