Particle Engineering For Respiratory Drug Delivery

Pulmonary illness rates are increasing and respiratory diseases. A critical quality attribute of inhalable powders is that they are in the 1-5 micron size range for optimum deposition in the lung. This executive summary contains (1) discussion of particle engineering approaches for inhaled compounds; (2) comparison of 'bottom-up' approaches-micronization-vs.'top-down' approaches such as spray drying; and (3) a case study of inhalable mannitol powders produced by micronization and spray drying. To learn more, read our executive summary.