ADCs / bioconjugates pose a complex challenge from a development and manufacturing perspective. We offer a complete end to end solution that simplifies the value chain and accelerates the timeline to the clinic or the market.
Our full-service offering for bioconjugates/ADCs provides you with:
- Early de-risking and optimization
- Process development and optimization
- Formulation development
- Analytical development
- Targeting agent or carrier protein
- Drug substance manufacture
- Drug product manufacture
- Payload and linker manufacturing
We have a successful track record of marketed bioconjugates, providing support through all stages of the lifecycle from concept to commercialization.
Our experience spans a broad range of technologies including:
- ADC’s
- AOC’s (Antibody Oligonucleotide Conjugates)
- Antibodies conjugated to nanoparticles (TNPs) and non-cytotoxic drugs (including peptides and polymers
- Conjugated duobodies
- Radio-immunoconjugates (mAb conjugated to chelating agents)
- Vaccines (haptens conjugated to carrier proteins)
- PEGylation and cross-linking
Our locations
Locations where this service is provided
Visp, Switzerland
Founded in 1897, Lonza today is a dedicated strategic manufacturing partner to the healthcare industry, working with customers in the pharma, biotech and nutrition markets. Visp remains our largest site in a global network of more than 30 sites and one of the most significant for research and development and manufacturing.
Our Visp site is a complex of industry-leading facilities specializing in the development and manufacture of products for pharmaceutical applications including mammalian and microbial biopharmaceuticals, small molecules, highly potent APIs, peptides and bioconjugates including antibody-drug conjugates (ADCs). It is also home to our pioneering Ibex® Solutions services offering. Ibex® Solutions enables customers to accelerate their path throughout the complete biopharmaceutical lifecycle - from preclinical to commercial stages, from drug substance to drug product, all in one location.