The bioconjugate market has made significant progress since the approval of the first antibody drug conjugate (ADC) in 2000.¹ Now, these innovative therapies make up approximately 10% to 15% of the biologics market.² Yet, despite the continued advancements in this space, drug developers pursuing bioconjugate modalities continue to face a wide range of challenges on their path to market. Experience, expertise, and a toolbox of solutions that can accommodate your product’s unique needs are critical in the early stages of development to mitigate risks later when the cost of failure is higher. Lonza Pharma & Biotech’s Dr. Raphael Frey, team lead for early development of bioconjugates, and Dr. Sandro Holzer, head of process development of bioconjugates, hosted the webinar From Early Development into Clinic – De-risking a Bioconjugate’s Journey. In it, Dr. Frey and Dr. Holzer discussed the challenges when moving a bioconjugate candidate from early development to clinic as well as key considerations for de-risking this journey. Two case studies were presented to demonstrate how Lonza has worked with clients to overcome obstacles in their path to the bioconjugate market. The following Q&A session was held after this webinar, where they addressed questions from attendees about how Lonza’s expertise and integrated solutions can help drug developers navigate this growing area of the biopharmaceutical industry.
Raphael Frey, Team Lead, Early Development, Bioconjugates
Sandro Holzer, Head of Process Development, Bioconjugates