Lead Scientist - Media R&D

United Kingdom, Slough

Today Lonza is a global leader in life sciences. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.

We have an opportunity for an experienced cell biologist with extensive knowledge of mammalian cell culture, cell line development, high throughput system and CHO cell biology to join our team of experts in Cell Culture Media Development as a Lead Scientist.

In this lab based role, you will join a fast-growing team that is purely focused on innovation and a unique opportunity to help cell culture media development projects in multidisciplinary and dynamic team.

Key responsibilities:

  • Working closely with Principal Scientist, Media R&D Slough; planning and prioritising tasks and assignments in a work program

  • Understanding and manipulating GS-CHO cell cycle regulation in vitro to develop cell culture media for producing biologically active proteins, monoclonal antibodies and biosimilars

  • Executing experimental plans, analyse experimental data, writes technical reports

  • responsibility for ensuring that studies are scientifically sound and in line with current regulatory guidance and expectations

  • Contributing to scientific expertise and propose new ideas and product concepts targeting the research market, drawn from scientific literature and personal experience

  • Ensuring GLP and EHS regulations are followed

Key requirements:

  • MSc in life sciences/related field and relevant industry experience

  • Technological background in mammalian cell line development and cell culture process development

  • Experience with high-throughput small scale bioreactors i.e., ambr15 and ambr250 in either a fed batch or perfusion capacity

  • Experience within Media Development preferred

  • Knowledge of mammalian CHO cell biology, cell cycle regulation, CHO cell metabolism

  • Experience with high-throughput systems and lab automation (integrated system)

  • In-depth knowledge of basic cell biology techniques, i.e., mammalian cell culture, Flow Cytometry, Western blotting, RT-PCR, confocal microscopy etc

  • Good understanding of upstream processes, including fed-batch and perfusion cultures

  • Knowledgeable of the current best practices for developing cell culture media including metabolomics, metabolic flux analysis

  • Strong interpersonal, presentation, time management, organizational and written/ oral communication skills are highly desirable

  • Inventiveness, enthusiasm, motivation, and problem solving skills to develop new technical capabilities and solve challenging problems

Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.


Reference: R44922
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