Senior Principal Scientist / Group Head Bioanalytics
Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.
Lonza is seeking a Senior Principal Scientist with relevant background in life sciences for our Bioanalytics group. If you bring a passion for bioanalysis and want to make a difference in your career apply now (on our homepage).
Lonza’s Drug Product Services team is highly skilled in the development of biopharmaceuticals including standard monoclonal antibodies, recombinant proteins, fusion proteins, antibody drug conjugates and vaccines, as well as viral- and cell-based therapies. The bioanalytics group will support development, validation and application of bioanalytical methods for release and stability testing of biologics under GMP. By applying various methods for measuring potency (ELISA/LBA, cell-based assays, Biacore, qPCR, etc.) we are an integral part of the analytical department to support our customer’s needs. In this position you will shape the strategy of bioanalytical projects and methods, and contribute to the future setup of the rapidly growing bioanalytical group, which is supporting projects for all disease areas and modalities, i.e. biologics, vaccines as well as cell and gene therapy.
Build, lead and manage a team of Group Leads and assigned Scientists within DPS Bioanalytics
Ensure effective use of resources of Group Leads and their Teams (time, personnel, equipment, material), maintenance of equipment, and follow lab instructions and all cGMP regulations
Liaise with partner units within the Lonza network to ensure the successful delivery of projects and Govern bioanalytical strategy for projects and life cycle management of bioanalytical methods
Review & Approval of reports throughout the life cycle of a project
Support Group Leads and their Teams by oversight of the design, establishment, optimization, and trouble-shooting of bioanalytical tests to support release, stability and formulation development, possibly under cGMP, following applicable SOP’s and all current documentation practices
Overall responsibility together with the Group Leads for the development and establishment of analytical methods and technologies as required (including ELISA, SPR, qPCR and cell-based, flow cytometry based potency assays and others). Oversee and engage in innovation and technical strategy projects
Establish DPS bioanalytical infrastructure and services for parenteral clinical and commercial products
Ensure safety and health protection – also for assigned Group Leads and Teams – by following lab and safety instructions and all cGMP regulations
Ph.D. in Biochemistry, Biotechnology or related Life Science subject
Working experience within the Bio-Pharmaceutical industry
Expertise and knowledge in several analytical methodologies, including lab automation, ligand binding assays (ELISA, HTRF, ECL), surface plasmon resonance, mammalian cell culture, preparation of primary cells, qPCR, flow cytometry, etc.
Passion for accurate documentation
Familiarity of working with electronic documentation systems (laboratory notebook, document management, LIMS)
Excellent communication skills.
Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.
People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.