Scientist

United States, Walkersville (Maryland)

Scientist

Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.

This position is part of a team that develops novel technology that supports Lonza’s allogeneic cell therapy manufacturing, such as 3D bioreactors, downstream processing of cells and/or exosomes, advanced analytical methods, etc. This is a hands on research job (75% lab based) where the scientist will be responsible for defining project targets, designing and executing experiments, analyzing data and drawing conclusions/next steps.

Key responsibilities:

  • Generating project targets based on the vision communicated by higher management, and designing experiments to achieve those targets.
  • Independently analyzing experimental data using statistics and graphing software, and communicating the findings to project team and executive committee level stakeholders.
  • Analysis includes drawing conclusions within the wider group and department context, hypothesizing mechanistic explanations of observed results, and proposing next steps.
  • Generating/updating timelines in MS Project.
  • Communicating findings on various levels, including: directly to manager, team updates, R&D group updates as well as interdisciplinary company forums and external meetings.
  • Writing and revising technical documents, maintaining accurate and up to date records, including appropriate lab notebook recordings, lab SOPs, test protocols and reports.
  • Management of potential academic collaborations to support exploratory feasibility studies.
  • Training new hires, interns, and collaborators (both internal and external) on the bioreactor platform.
  • Perform administrative tasks or other duties as needed.

Key requirements:

  • 5 - 7 years of experience in Biology as an independent researcher.
  • Master’s in Biology, bio or chemical engineering, biotechnology.
  • PhD in Biology, bio or chemical engineering, biotechnology.

Knowledge Required:

  • Cell/Molecular biology and basic biochemistry
  • Fundamentals of human cell culture and molecular biology
  • Strongly preferred:
  • Understanding of cell therapy and therapeutic exosomes (cell types, diseases targeted)
  • Expertise in technologies for the isolation and characterization of extracellular vesicles, including exosomes.
  • Data analysis/statistics

Desirable:

  • Background in bioprocess engineering, especially bioreactors and downstream techniques
  • Developmental biology/regenerative medicine
  • Closed processing systems

Skills Required:

  • Aseptic technique / work with BSC level 2
  • Human cell culture and isolation
  • Excellent oral/written/presentation communication skills; strong work ethic; delegating skills; ability to perform in a team setting

Strongly preferred:

  • Exosome isolation and analysis
  • FACS
  • ELISA
  • qPCR, digital PCR
  • NTA, Nano FCM or similar for nanoparticle characterization
  • Bioreactor operation
  • Design of Experiment

Desirable:

  • Bioprocess scale-up
  • Assay development (detection assays, functional assays)
  • Automation (liquid handlers, robots, control systems)
  • Continuous processing (e.g. separation)

                Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

                People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.

                Lonza is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a qualified individual with disability, protected veteran status, or any other characteristic protected by law. 

Reference: R36353
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