Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.
We are currently looking for a Lead Scientist to join our team based on our manufacturing site in Slough, UK. The purpose of this position is to provide scientific leadership on projects including but not limited to standard monoclonal antibody purification process, purification, process transfers (from Customer or between Lonza sites), recombinant purification process development, Downstream process characterisation and process validation studies to support License Applications. You will be required to proactively identify opportunities for process improvement and lead specific improvement projects. You will represent Purification Development at project team and Customer meetings and take an active role in the generation of Proposals for new and existing Customers.
Application of regulatory guidelines to experimental design
Design and execution of standard and non-standard mAb Evaluations
Design and lead bespoke and complex stages or projects
Responsible for execution of Laboratory work for own project or to support others
Competently plan and direct the work of others
Coach, mentor and train more junior members of department as required
Study Director for Process Characterisation Studies and Validation Studies
SME for regulatory inspections
Established as SME in particular area
Competently lead and be accountable for the delivery of multiple projects (focusing on safety, quality, right first time, on time delivery) and additional responsibilities to agreed timelines including creation and completion of project dashboards
Collate, analyse and evaluate data from work / study programs and offer advice when required
Write, review and critique reports to an agreed standard suitable for final review by Head of Department
Prepare and deliver presentations, protocols and reports with right first time quality
Engage with Customers to demonstrate Lonza’s scientific credibility and grow relationships
Escalate risks and issues in a timely fashion (technical, resource, Customer, cost)
Lead problem solving / trouble shooting / lessons learned activities
Primary technical contact for Customers for ongoing projects and Develop Customer relationships Engage with Customers to demonstrate Lonza’s scientific credibility and grow relationships
Role model for communication, best practice and behavior within Process Development
Input into Customer proposals (technical content and man days)
Identify opportunities and proactively input into departmental and process improvements and lead specific improvement projects and investigations
Proactive approach to own continuous professional development
Conduct Customer Laboratory Tours
Represent Lonza externally
Demonstrate flexibility to support other activities within the team/department
On call rota
System maintenance / System owner
Raise and Lead equipment Change control
Execute allocated duties consistent with cGMP and EHS policies and standards
Maintain required training and skills to execute duties
Contribute to departmental training
Demonstrates a high level of independence
Manage and prioritise multiple tasks
Phd or BSc in relevant scientific / technical discipline and appropriate experience
In depth knowledge of all relevant service offerings
The ability to assimilate complex information and draw insightful conclusions
Established credibility within the Lonza network or broader scientific network
Keen appreciation of commercial requirements
Ability to set clear direction and goals
An excellent understanding of the theory and practice of protein purification and protein structure is required.
In depth theoretical knowledge and practical experience in downstream processing e.g; AKTA Chromatography systems, Ultra-filtration, high throughput resin screening etc
Experience in purification of recombinant proteins (including but not limited to monoclonal antibodies)
Some knowledge of GLP/GMP or similar quality systems
An awareness of technology transfer of processes from laboratory scale to manufacturing plants.
Process Validation experience in line with current regulatory guidelines
Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.
People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.