Biotechnologist, Cell & Gene Technologies

Singapore, Tuas Singapore

Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.

Did you know that we are the 1st biologics contract manufacturer in Singapore? We offer you exposure to upcoming biotech and established pharmaceutical companies and to the manufacturing technology needed to produce mammalian treatments and cell therapies of tomorrow. Our global manufacturing network is recognized for its reliable, high-quality services, regulatory track record, global footprint, innovative technology platforms and extensive experience – we, in Singapore are proud to be part of this global network.

As our Cell & Gene Technologies (CGT) business grows, we are looking to further strengthen our manufacturing team in Tuas, Singapore. You will be responsible for the manufacture of therapeutic cell products under current Good Manufacturing Practice (cGMP) conditions. Working closely with a team of Technical personnel and Subject Method Experts, CGT Biotechnologists are expected to execute cGMP Cell Therapy production activities through to filling of final dose product within a stringent cGMP clean room environment.

As a member of the Cell & Gene Technologies Manufacturing team, the aim of this position is to develop expert technical knowledge and flawless execution of the Cell Therapy production process. This position could be an ideal opportunity for someone with an interest in Cell Therapy wanting to develop their production career in a different technical/scientific area.

You will be working in 12-hour rotating shift in a 2-2 3-2 2-3 pattern and will be compensated with shift premium and allowances!

Key responsibilities:

  • Complies with site/department EHS standards (policies, rules and regulations)

  • Attains a thorough understanding of the principles of cGMP compliance and clean room practices

  • Contributes to appropriate maintenance of ‘in-operation’ production facilities and equipment e.g. cleaning & sanitization, equipment monitoring, sampling, pH and conductivity checks

  • Solution and medium preparation followed by aseptic filtration into sterile containers

  • Revival and culturing of anchorage dependent cell lines in static flasks and cell factories

  • Harvest and concentration of cell factory generated cell cultures using tangential flow filtration or/and centrifugation

  • Final formulation and filling of vials

  • Visual inspection and cryopreservation

  • Participation in Aseptic Process Simulations

  • Accurate and thorough completion of batch record documentation

  • Environmental monitoring (viable particulates, non-viable particulates, surface and operator)

  • Formulation of media and aseptic filling of media bags and bottles

Key requirements:

  • Diploma / Degree in Science disciplines or working experience in biopharmaceutical industry or semi-conductor cleanroom environment

  • Knowledge of cell culture and the principles of aseptic processing within a classified environment is not essential, but an advantage

  • Strong team oriented work ethic

  • Attention to detail

  • Planning, Organizing, & Controlling

  • Effective Communication - clear and concise (both written and oral)

  • Professional

  • Team player

  • Flexible

  • Willing to perform rotating 12-hour shift pattern

Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.

Vaccination status: As the above role requires you to work on-site*, only fully vaccinated** employees will be shortlisted for the role.  For fully vaccinated applicants, please indicate your vaccination status as “fully vaccinated” when applying for the role.

*In line with the latest advisory from the Ministry of Manpower, from 1 January 2022 only employees who are fully vaccinated or have recovered from COVID-19 within the past 180 days, can return to the workplace.

** Lonza adopts the definition of “fully vaccinated” by the Ministry of Health in Singapore which means that you:

(a) have received the full regimen of WHO EUL vaccines from a specific manufacturer; and

(b) have met the prescribed post-vaccination period for the respective vaccine to be fully effective.

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Reference: R22856