Significantly decreased post-physical activity joint discomfort among healthy subjects aged 20-55 years1
Improved knee extension by 10% compared with baseline in the UC-II® group2
15X better range of motion when compared to placebo
(3.23 degrees vs. 0.21 degrees)2

Empower active lifestyles with UC-II® undenatured type II collagen

UC-II® undenatured type II collagen is the most researched undenatured type II collagen brand that is clinically studied to maintain or support joint comfort and mobility with one small daily dose of 40mg.

With more consumers prioritizing their health for the long-term, there is an opportunity for your brand to support a new generation of younger, active adults.

Product features

  • Unique mechanism of action - helps support the body’s natural cartilage repair process and promotes normal building of new cartilage5-7.
  • Animal studies suggest that the likely mechanism of action promotes normal inflammatory response while helping to support cartilage regeneration.
  • Low dose - unsurpassed consumer convenience with just one small 40 mg daily dose1-4.
  • Can be formulated in a wide range of in-demand dosage forms8.

Disclaimer: Unless otherwise expressly stated herein, these statements have not been evaluated by any competent authority, including the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. This is business-to-business information intended for food and supplement producers, and is not intended for the final consumer. This information is based on our own research and development work and is, to the best of our knowledge, reliable. However, Lonza does not assume any liability of risk involved in the use of this information, as conditions or use are beyond our control. Manufacturers should check local regulatory status of any claims according to the intended use of their products and are solely responsible for the marketing of their finished products in accordance with all applicable laws.

Premium ingredient that meets leading market demands in the joint health and active lifestyle categories

We are committed to providing high-quality ingredients and formulations, as evident by our NSF GMP Registration Program Requirements of NSF/ANSI 173, Section 8 which includes FSMA and cGMP (21 CFR 111, 21 CFR 117).

Learn more about our products made with your consumer’s needs in mind.

Product features

Also available in different grade:

  • UC-II® Pets
  • UC-II® Halal
  • UC-II® Non-GMO

*Grade availability differs by region

The most researched brand of undenatured type II collagen

UC-II® undenatured type II collagen is backed by the most comprehensive body of evidence-based research, spanning over two decades and over twenty studies, including eleven human clinical studies.

Research including healthy and active consumers, aged 20-55 years, found that a 40 mg daily dose of UC-II® undenatured type II collagen improved joint flexibility by three degrees - 15 times more effectively - than the placebo1.

Supplementation also reduced joint discomfort after physical activity, improved knee comfort when moving and supported people’s ability to hit their daily step goals1.

These findings present a huge benefit for brands to turn cutting-edge science into real opportunities for consumers.

Product features

  • Supports joint flexibility and comfort
  • Proven efficacy in healthy adults 20-55
  • Helps consumers meet their daily step goals

Supporting you through every step of the launch process

Offering complete concept-to-market services, we ensure your products are well-made and well-positioned within the nutraceuticals market. From creating your perfect formulation to getting your product on the shelves quickly, our experts can help you create a tailored solution.

Service features

  • Get to market faster
  • Easily fill portfolio gaps
  • Capitalize on market trends

Upgrade your joint supplement

UC-II® undenatured type II collagen offers unsurpassed convenience with just one small 40 mg daily dose. It also works across a wide range of in-demand dosage forms, from capsules to functional foods8.

Product features

  • Supports joint comfort better than glucosamine and chondroitin3
  • Safe and well tolerated

UC-II® undenatured type II collagen is the next generation joint health ingredient, clinically studied to help reduce joint discomfort and improve flexibility and mobility in healthy, active adults1-3.

Unlike hydrolyzed collagen which requires a large daily dose (up to 20,000 mg a day) and glucosamine and chondroitin, UC-II® undenatured type II collagen supports joint health with just one small 40 mg dose per day1-5.

Fuel the new era of active lifestyle consumers with a different form of collagen

Clinically-proven benefits

The most researched brand of undenatured type II collagen*