A spawning pair of horseshoe crabs returns to sea at sunrise.

New in 2015:
Explore the World of Horseshoe Crabs


A Living Fossil

The selected cover image shows a spawning pair of horseshoe crabs returning to the sea at sunrise, captured on Pickering Beach, Delaware. The horseshoe crab’s annual spawning ritual has repeated itself on beaches for over 450 million years.

Lonza is aware of the importance of the horseshoe crab, both for its contribution to the safety of drugs and medical devices, but also its ecological role. LAL, Limulus Amebocyte Lysate, derived from the blood cells of the horseshoe crab, is used for Quality Control (QC) tests for vaccines, injectable drugs and implantable medical devices.

Close at hand, may this Notebook serve as a gentle reminder of this amazing animal and its contribution to global health, as well as the need to explore alternative methods for endotoxin testing.

With Special Thanks to ERDG

We extend our sincere appreciation to Glenn Gauvry, President and Founder of ERDG, the Ecological Research and Development Group, for his education into the world of this ancient mariner and for his collaboration on our Notebook Project.

To learn more about horseshoe crab conservation and Lonza’s best practices in the harvesting and handling of the horseshoe crabs that are used in the manufacturing of LAL, please visit: lonza.com/hsc.