Image of white blood cells and red blood cells

Purified cells from human cord blood. 

Viable cell count and purity claims are guaranteed. 

Use HPGM™ Medium for optimal performance. 

Umbilical cord blood is a rich source of hematopoietic stem cells and provides an intriguing avenue into potential therapies for various diseases. For example, there is great potential for cord blood cells to provide the solution to HLA-mismatch issues in clinical transplantation. In fact, cord blood lymphocytes have been found to be phenotypically and functionally immature, suggesting they may not be as capable of mediating graft-versus-host disease as bone marrow or peripheral blood derived cells1.

The cellular composition of umbilical cord blood is very similar to bone marrow and includes hematopoietic stem (HSCs) and progenitor cells (CD34+ cells and CD133+ cells), lymphocytes, monocytes, and mesenchymal stem cells.

The number of stem cells present in umbilical cord blood is finite, resulting in one of the major limiting factors in the clinical utility of cord blood cells. However, there are currently studies focused on ex-vivo expansion of specific cord blood cell types in an effort to mitigate the small number of available cells per cord1.

The distribution of umbilical cord blood is tightly regulated, thus access to cells might pose issues in your research. To address this concern, Lonza has an established umbilical cord tissue acquisition program, so you can have easy access to the cord blood cells you need for your research.

In addition, Lonza understands the importance of being able to compare and contrast characteristics and functions of cells from various donors, which is why most cell types are available from a variety of donors. Lonza Scientific Support Specialists are readily available to answer questions you have about obtainable donor characteristics.

Lonza Poietics™ purified cord blood cells include:


Cord blood cells are guaranteed to have at least the number of viable cells claimed by each product number, and purity levels are verified via flow cytometric analysis.


References:

1. Umbilical cord blood research: Current and future perspectives. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720821/

Lonza guarantees the performance of Clonetics™/Poietics™ cells only if appropriate Clonetics™/Poietics™ media and reagents are used exclusively and the recommended storage and use protocols are followed. any modifications made to the recommended cell systems including use of alternative media, reagents or protocols, will void cell and media performance guarantees. If you need assistance in selecting the appropriate media, reagents, or protocol, please contact Lonza Scientific Support.