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Measure bone resorption in minutes
The OsteoLyse™ assay kit provides an easy to use protocol for quantitatively measuring in vitro osteoclast-mediated bone resorption in a high-throughput format. Osteoclasts can be seeded onto the OsteoLyse™ plate using traditional cell culture protocols. The assay directly measures the release of Europium-labeled collagen fragments into the osteoclast cell culture supernatant via time resolved fluorescence, indicating their resorption activity levels.
Kit includes 96-well plate with collagen, Fluoropore Releasing Reagent, and an empty 96-well assay plate.