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Archived Webinar: Hepatocytes in the Drug Development Pipeline
Fresh Human Hepatocytes
Triangle Research Laboratories (TRL), now part of Lonza, provides fresh human hepatocytes isolated from whole and resected liver tissues. The availability of these tissues is difficult to predict. If you would like to be notified of fresh human hepatocyte isolations, please sign up for our FreshAlert list.
Primary fresh human hepatocytes can be used for a variety of in vitro applications, including, but not limited to:
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Cryopreserved Human Hepatocytes
Every lot of human cryopreserved hepatocytes is characterized for post-thaw viability and yield, plateability (adherence to a collagen-coated surface), and some combination of Phase I and Phase II drug metabolizing enzyme activities, inducibility, and uptake and efflux transporter activity—documented in a certificate of analysis. We have a wide selection of lots that can be used for a variety of applications, including, but not limited to:
All suspension qualified human cryopreserved hepatocytes are characterized for CYP450 and Phase II drug-metabolizing enzyme activity. Both single donor and pooled human cryopreserved hepatocytes can be used for a variety of applications including metabolic stability, intrinsic clearance, metabolite ID, metabolite profiling, species comparison studies, and uptake transporter studies.
The Utility Of Primary Human Hepatocytes In The Drug Development Pipeline
Dr. Salman Khetani discusses various primary hepatocytes models in the drug development pipeline.
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Cryopreserved Human Hepatocytes for Plated Applications
Interested in custom cells? Learn about custom cell preparation options.
Related Products: Intestinal Cells, Renal Cells, Lung Cells, Neurons, Dermal Cells
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