Advantages of Microreaction Technology

  • Introduction

    Small Footprint, Large Impact

    The majority of leading pharmaceutical and fine chemical companies are investing in microreaction technology (MRT) due to the significant advantages it offers for development and scale-up. In addition, Lonza’s FlowPlate® Microreactors require less space and CAPEX investment and also provide safer processing conditions for highly reactive and toxic compounds.

    Lonza’s Microreaction Technology has been shown to reduce cost of goods, while increasing yield and productivity.
  • Yield and Productivity

    Due to rapid mixing, excellent heat exchange, and exact control of residence time, reaction selectivity is improved with microreaction technology, which increases overall process yield. In addition, a broader design allows for the ability to explore new conditions for drastic process intensification.

    This technology can be automated, requiring less manpower. The resulting reduction in human error leads to improved productivity. It also improves facility throughput by providing faster change-over, using a modular concept and a toolbox  approach.
  • Cost of Goods

    Lonza uses an advanced approach to microreaction technology known as Flash Chemistry, where multiple steps of a traditional chemical process can be replaced by a single Flash Chemistry step.  This leads to shorter synthetic routes and reduced processing time, which ultimately reduces cost of goods. Use of Flash Chemistry also creates processes that are inherently safer due to the high level of containment of high temperature and pressure reactions. Microreactors provide safer processing conditions for highly reactive and toxic compounds, which improve environmental impact, leading to lower cost of goods.

     

    *Flash Chemistry refers to a concept based on high-resolution reaction time control using flow microreactors, which enables chemical reactions that cannot be done in batch and serves as a powerful tool for laboratory synthesis of organic compounds and for production in chemical and pharmaceutical industries.
    See: Yoshida, J.-l.et al., Chemistry - A European Journal 2008 (14) 7450